Cancer Biology

di Ruddon • 2007 • dettagli prodotto

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DESCRIZIONE

A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological changes that occur in tumour tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behaviour. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography.Table of Contents1. Characteristics of Human Cancer2. Causes of Cancer3. The Epidemiology of Human Cancer4. The Biochemistry and Cell Biology of Cancer5. Molecular Genetics of Cancer6. Tumor Immunology7. Cancer Diagnosis8. Sequelae of Cancer and Its Treatment9. Cancer Prevention