Basic Concepts of Molecular Pathology

di Cagle - Allen • 2009 • dettagli prodotto

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DESCRIZIONE

The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine.Table of contents / Sample pages Genes, Gene Products, and Transcription Factors.- Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair.- Cell Adhesion Molecules.- Apoptosis and Cell Death.- Mutations and Epimutations.- Bioinformatics and Omics.- General Approach to Molecular Pathology.- Applications of Molecular Tests in Anatomic Pathology.- Polymerase Chain Reaction and Reverse Transcription-Polymerase Chain Reaction.- Array Comparative Genomic Hybridization in Pathology.- Loss of Heterozygosity.- In Situ Hybridization.- Proteomics.- Immunohistochemistry of Biomarkers.- Flow Cytometry.- Stem Cells.- Animal Models of Disease.- Tissue Culture Models.- Index.