Churchill' s In Clinical Practice Series - Diabetes and The Heart

di Barnett - O'Gara • 2003 • dettagli prodotto

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DESCRIZIONE

The In Clinical Practice series aims to provide expert information 'at your fingertips' - concise handbooks organised in a straightforward way. Dr Barnett runs one of the largest diabetes clinics in the UK, and the book addresses the strong link between type II diabetes and cardiovascular disease. Cardiac disease is the leading cause of diabetes-related deaths, and the book includes discussions on the scale of the problem, co-occurrence of risk factors, and symptoms such as dyslipidaemia, hypertension and glycaemia. Also discussed is the importance of the metabolic or insulin-resistant syndrome. Key clinical trials are covered, and there are chapters on Treatment and Future DevelopmentsContentsIntroduction and background - scale of the problem of diabetes; reasons for exponential rise in numbers; overview of vascular complications.Definition and epidemiology - diabetes and cardiovascular disease focus on the heart scale of the problemAetiology - importance of metabolic (insulin resistance) syndrome. Co-occurrence of risk factors for atherogenesis and vascular diseaseObesityLipidsHypertensionGlycaemiaSmokingDiagnosis - diabetes is a cardiovascular disease risk factor screening low threshold for investigations tools for investigationPrevention - evidence base for treatment key clinical trialsTreatment - obesity, dyslipidaemia, hypertension, glycaemia, lifestyle adviceFuture developments - emphasis on care pathways algorithmic approaches treating to target new uses for established therapies (e.g. glitazones, rapid acting insulin secretagogues)Clinical cases