Biology and Pathology of Trophoblast

di Moffett - Loke - McLaren • 2006 • dettagli prodotto

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DESCRIZIONE

This is the first dedicated, in-depth account of trophoblast: the tissue derived from the fertilized egg that nourishes and protects the developing fetus. Disorders of trophoblast during development manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia.Table of Contents Preface Charlie LokeChair's introduction Anne McLaren1. Trophoblast cell fate specification: discussion James Cross2. Stem cells: pluripotency and extraembryonic differentiation in the mouse Tilo Kunath3. Epigenetic regulation of trophoblast development P. Hajkova, S. E. Erhardt and M. A. Surani4. Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis Neil Brockdorff5. Gestational Trophoblastic disease R. A. Fisher and N. J. Sebire6. Trophoblast and the first trimester environment Graham J. Burton, Eric Jauniaux7. Implantation is a sticky situation Olga Genbacev, Akraporn Prakobphol, Russell A. Foulk and Susan J. Fisher8. Trophoblast regulation of maternal endocrine function and behaviour E. B. Keverne9. Molecular signalling in embryo-uterine interactions during implantation S. K. Dey and Susanne Tranguch10.Trophoblast and pre-eclampsia C. W. G. Redman, I. L. Sargent and E. A. Linton11. Trophoblast and uterine mucosal leukocytes Ashley Moffett12. Immunology of trophoblast: a reappraisal Charlie Loke