Modern Surgical Neuropathology

di Miller • 2009 • dettagli prodotto

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DESCRIZIONE

The nervous system constitutes arguably the most complex organ system in the human body, which contributes to the over-susceptibility of disease in this area. Although brain tumors were once an automatic death sentence, the outlook for recovery has brightened significantly in the past decade. The pathologist plays an indispensable role in surgical diagnosis; he or she must accurately diagnose a potentially wide array of disease entities, determine the spread of disease within millimeters, and assess patient prognosis. This new and modern reference in neuropathology comprehensively covers all the methods used by pathologists to accurately diagnose a wide array of neurologic illnesses. Brain and spinal cord tumors are the predominant focus, but a full spectrum of infectious, inflammatory, and congenital disorders are also covered in detail, in both pediatric and adult populations, with a full range of diagnostic modalities. The book is illustrated with more than 1,200 full-color photomicrographs and accompanied by a CD-ROM of all images in a downloadable format.Table of Contents 1. Introduction and overview: principles and techniquesPart I. NeoplasmsSection 1. Brain Neoplasms: Subsection 1. Intrinsic Brain Tumors: 2. Gliomas: an overview3. Diffuse fibrillary astrocytomas4. Special types of astrocytomas5. Oligodendroglioma6. Mixed gliomas7. Ependymomas8. Neuronal and neuronal-glial tumors9. Primitive neuroectodermal tumors10. Primary CNS lymphomas11. Primary CNS germ cell neoplasms12. Hemangioblastoma13. Choroid plexus neoplasms14. Metastatic neoplasms in the bran parenchymaSubsection 2. Extrinsic Brain Tumors: 15. Meningiomas16. Nonmeningioma dural-based neoplasms17. Dura and leptominingeal metastatic cancer18. Tumors of intracranial peripheral nerves19. Craniopharyngioma and Rathke's cleft cysts20. Miscellaneous meningeal masses21. Pituitary tumors22. Skull-based neoplasmsSection 2. Spinal Cord Neoplasms: Subsection 1. Intrinsic Spinal Cord Tumors: 23. Intrinsic spinal cord tumors: overview24. Ependymomas of the spinal cord25. Other gliomas of the spinal cord26. Miscellaneous cord tumorsSubsection 2. Extrinsic Spinal Cord Neoplasms: 27. Meningiomas and other primary dural-based tumors of the spinal cord28. Nerve root tumors29. Tumors of the spinePart II. Non-Neoplastic Mass Lesions: 30. Tumefactive demyelinating disease31. Inflammatory masses in the brain parenchyma32. Extra-axial inflammatory/infectious lesions33. Biopsies of cerebral infarcts34. Extra-axial intracranial hemorrhages35. Vascular malformations of the CNS parenchymaPart III. Diagnostic Brain Biopsies for Non-Neoplastic Disease: 36. Biopsies for vasculitis37. Biopsies with/for non-inflammatory vascular diseases38. Biopsies for diagnosis of dementia39. Biopsies for infectious diseasesPart IV. Surgical Neuropathology of Epilepsy: 40. Current procedures leading to epilepsy surgery: what the neuropathologist should know about the epilepsy work-up prior to surgery41. Abnormalities presumably causing epilepsy42. Effects of epilepsy manifest in resected brain tissue43. Iatrogenic lesions44. Special syndromes and epilepsy