Multiple Sclerosis - A Comprehensive Text

di Raine - McFarland - Hohlfeld • 2008 • dettagli prodotto

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DESCRIZIONE

Multiple sclerosis has rapidly changed over the last decade into a condition necessitating a multi-disciplinary approach to both its management and understanding. This book reflects all these advances including contributions from genetics, immunology and molecular biology. The many new drugs, both approved or in advanced stages of clinical trials, which give cause for optimism for the treatment of the disease, are described. This new comprehensive work has both editors and contributors that bring together basic science researchers and clinicians from Europe and the USA. History of MS. Clinical features of MS. Unusual presentations of MS. Differential diagnosis of MS. Imaging of MS. Paraclinical features of MS (EP, CSF etc). Natural history of MS. Multiple sclerosis and pregnancy. Neuropathology of MS (histology/immuno/EM). Pathophysiology of MS. Immunology of MS. Genetics of MS. Viruses and MS. EAE - a model for MS. Development of myelin. New research tools for MS. Approved therapies and management of MS. Escape therapies and management of MS. Emerging therapies for MS. Therapeutic strategies for MS. Symptomatic strategies for MS. Sexual and bladder dysfunction in MS. Neuropsychological testing in MS. Rehabilitations of MS. Design of clinical trials in MS. Role of DSMBs in clinical trials in MS. Outcome measures in MS