Tumour - Associated Macrophages
di Lawrence - Hagemann • 2011 • dettagli prodotto
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DESCRIZIONE
Macrophages are tissue resident phagocytes that have important roles in development and immunity. The observation that cancers become infiltrated by large numbers of macrophages was first made by Virchow in 1863, clinical and experimental studies suggest tumor-associated macrophages (TAM) are critical to promote carcinogenesis and tumor-progression, however to this day it still isn’t clear what regulates the recruitment of macrophages in tumors and what drives their pro-tumor functions. This volume will provide an overview of current research on the form and function of TAM, highlighting both the mechanistic roles they play in carcinogenesis and tumor progression as well as the molecular mechanisms that control their phenotype and function, and the final chapter addresses the issue of TAM as a potential target in cancer therapy.
DETTAGLI PRODOTTO torna su
ISBN: 9781461406617
Titolo: Tumour - Associated Macrophages
Autori: Lawrence - Hagemann
Editore: Springer Verlag
Volume: Unico
Edizione: 2011
Lingua: Inglese
Finitura: Copertina flessibile
Pagine: 338
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