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DESCRIZIONE
Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
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ISBN: 9789400724174
Titolo: Neuroblastoma
Autori: Hayat
Editore: Springer Verlag
Volume: Unico
Edizione: 2011
Collana: Pediatric Cancer - Vol 1
Lingua: Inglese
Finitura: Copertina rigida
Misure: 18x25 cm
Pagine: 123
Peso: 0.7 kg
RECENSIONI
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