Organofluorine Compounds in Biology and Medicine

di Reddy • 2015 • dettagli prodotto

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DESCRIZIONE

Organofluorine compounds, due to their unique physical and chemical properties, are increasingly adapted as therapeutics for a variety of human diseases and in studies related to biochemical processes.
The extraordinary potential of fluorine-containing biologically relevant molecules in biology, medicinal chemistry, and medical applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is expanding its biomedical frontiers. This book contains cutting-edge developments and future prospects of fluorine in bioorganic and medicinal chemistry. It is essential for researchers who want to take advantage of the use of fluorine in biomedical research, from rational drug design, theory and synthesis to the use of fluorine labels as probes in metabolic study, protein engineering, and clinical diagnosis
Although there are several books dedicated to synthesis and material applications of organofluorine compounds there have been no major reference books on the biological and medicinal applications of organofluorine chemistry in recent years. One of the related books was published by Elsevier in 1993 (Organofluorine Compounds in Medicinal Chemistry and Biomedical Applications).
This book will cover topics on biochemically relevant organofluorine compounds, and their synthesis and mechanistic pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to scientific community involved in this area.
Although it is too early to say if it can be adapted as a text book by many universities as the contents of the book will be more specialized, it would certainly serve as a reference book for courses in organic synthesis, advanced organic chemistry, and courses in biochemistry.