normalmente disponibile
per la spedizione in 20-25 giorni lavorativi
da
a
€ 186,99
DESCRIZIONE
This book provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards outcome prediction, but these innovations are insufficiently applied in medical research. Old-fashioned, data hungry methods are often used in data sets of limited size, validation of predictions is not done or done simplistically, and updating of previously developed models is not considered. A sensible strategy is needed for model development, validation, and updating, such that prediction models can better support medical practice. Clinical prediction models presents a practical checklist with seven steps that need to be considered for development of a valid prediction model. These include preliminary considerations such as dealing with missing values; coding of predictors; selection of main effects and interactions for a multivariable model; estimation of model parameters with shrinkage methods and incorporation of external data; evaluation of performance and usefulness; internal validation; and presentation formats. The steps are illustrated with many small case-studies and R code, with data sets made available in the public domain. The book further focuses on generalizability of prediction models, including patterns of invalidity that may be encountered in new settings, approaches to updating of a model, and comparisons of centers after case-mix adjustment by a prediction model.
DETTAGLI PRODOTTO torna su
ISBN: 9780387772431
Titolo: Clinical Prediction Models - A Practical Approach to Development, Validation, and Updating
Autori: Steyerberg
Editore: Springer Verlag
Volume: Unico
Edizione: 2009
Collana: Statistics for Biology and Health
Lingua: Inglese
Finitura: Copertina rigida
Pagine: 500
RECENSIONI
NESSUNA RECENSIONE PER QUESTO PRODOTTO